Whitney Kramer

Whitney Kramer is a pre-doctoral student training in pharmacometrics and bioethics/health policy through the Division of Clinical Pharmacology at Indiana University.  She is jointly mentored by Dr. Eric Meslin, the Director of the Center for Bioethics and former Executive Director of the National Bioethics Advisory Commission under President Clinton, and Dr. Robert Bies, the director of the Disease and Therapeutic Response Program of the Indiana Clinical and Translational Sciences Institute and scientific adviser to the Metrum Institute, a hub for pharmacometricians developing the software and training programs for integrating simulation into improving the efficiency of drug development.  This unique pairing of an ethicist and a scientist provides strong scientific mentorship as well as mentorship in translating science to improve health.  Our team is specifically focused on re-evaluating the scientific merits and ethical acceptability of post-market clinical trials of prescription drugs.

Whitney’s prior experiences include:

Clinical research with the Ring 20 Foundation at the Children’s Hospital of Philadelphia/University of Pennsylvania.
Health policy research in personalized medicine at the Center for American Progress
Pharmacogenomics research of copy number variation at the Mayo Clinic

Publications:

Michael Rugnetta and Whitney Kramer (September 2009). Paving the Way for Personalized Medicine: Facilitating inter-agency coordination for the integration of personalized medicine into our healthcare system. Science Progress. Available from: http://www.scienceprogress.org/2009/09/personalized-medicine/

This proposal has been incorporated into HR5440: Genomics and Personalized Medicine Act of 2010.

Laura Conlin, Whitney Kramer, Anne Hutchinson, Xia Li, Harold Riethman, Hakon Hakonarson, John Mulley, Ingrid Scheffer, Samuel Berkovic, Syed Hosain, and Nancy Spinner  (November 2010).  Molecular Analysis of Ring Chromosome 20 Syndrome Reveals Two Distinct Groups of Patients.  Journal of Medical Genetics. PMID: 20972251

Whitney E. Kramer, Denise L. Walker, Dennis J. O’Kane, David A. Mrazek, Pamela K. Fisher, Brian A. Dukek, Jamie K. Bruflant , John L. Black III (October 2009). CYP2D6: Novel genomic structures and alleles. Pharmacogenetics and Genomics. PMID: 19741566