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Cluster Randomized Clinical Trials: Ethics and Science

Cluster Randomized Clinical Trials: Ethics and Science

Introduction:

On March 29th, 2017, Edward Liechty, MD, Professor Emeritus of Pediatrics at the Indiana University School of Medicine, gave a presentation on the unique ethical issues that arise from cluster randomized clinical trials. Dr. Liechty's presentation, "Cluster Randomized Clinical Trials: Ethics and Science," differentiates between individual and cluster trials and analyzes the power of each type of study. This talk helps the viewer determine the pertinent bioethical issues in cluster randomized clinical trial set-up, such as: personal autonomy, community representation, and a researcher's scope of authority.

References:

Download the transcript for this TREATs talk here.
London, A., Taljaard, M., Weijer, C. (2020). Loopholes in the Research Ethics System? Informed Consent Waivers in Cluster Randomized Trials with Individual-Level Intervention. Ethics & Human Research, 42(6).
McRae, A., Weijer, C. Minik, A. et al. (2011). When is Informed Consent Required in Cluster Randomized Trials? Trials. 12, 202.
Weijer, C. et al. (2011). Ethical Issues Posed by Cluster Randomized Trials in Health Resarch. Trials, 12, 100.

Cluster Randomized Clinical Trials: Ethics and Science