Dr. Lauren Nephew is Assistant Professor of Medicine in the Division of Gastroenterology and Hepatology and the Associate Vice Chair of Health Equity for the Department of Medicine at Indiana University School of Medicine. Her NIH-funded research program focuses on understanding how the structural and social determinants of health contribute to disparities in liver disease and developing interventions that improve access to liver transplantation.
Dr. Nephew completed Internal Medicine residency at Massachusetts General Hospital and Gastroenterology and Liver Transplantation Fellowships at the University of Pennsylvania. While at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University for medical school, Dr. Nephew completed a Master’s program in Bioethics. While at the University of Pennsylvania, she completed a Master’s of Science in Clinical Epidemiology.
Inpatient Service Teaching - Indiana University Hospital
Selected Guest Lectures:
Hepatitis C Treatment Allocation - Gastroenterology and Nutrition - IUSM
Ethics of Liver Transplantation - Gastroenterology and Nutrition - IUSM
- Health Equity
- Transplantation Ethics
- Racial Disparities in Hepatocellular Carcinoma
- Alcoholic Hepatitis
- Nephew LD, Gupta D, Carter A, Desai AP, Ghabril M, Patidar KR, Orman E, Dziarski A, Chalasani N. Social determinants of health impact mortality from HCC and cholangiocarcinoma: a population-based cohort study. Hepatol Commun. 2023.
- Mohamed KA, Ghabril M, Desai A, Orman E, Patidar KR, Holden J, Rawl S, Chalasani N, Kubal CS, D Nephew L. Neighborhood poverty is associated with failure to be waitlisted and death during liver transplantation evaluation. Liver Transpl. 2022.
- Patidar KR, Naved MA, Grama A, Adibuzzaman M, Aziz Ali A, Slaven JE, Desai AP, Ghabril MS, Nephew L, Chalasani N, Orman ES. Acute kidney disease is common and associated with poor outcomes in patients with cirrhosis and acute kidney injury. J Hepatol. 2022.
Additional Publications: PubMed
Alcoholic Hepatitis Clinical and Translational Network Late Phase Clinical Trials and Observational Studies (Co-I)
$343,426 annually from the NIH & NIAAA 2018-Present
Description: The purpose of this research study is to create a clinical database and bio-repository. To do this, biological samples and personal health information from participants will be obtained to use in future research studies related to alcoholic hepatitis or other diseases. This work is funded by the National Institutes of Health and the National Institute on Alcohol Abuse and Alcoholism.
K23 Award: Overcoming Disparities in HCC; HCC-EduLink Intervention (PI)
$150,000 annually from the NIH & NMHDI 2022-2026
Description: The purpose of this research study is to develop an intervention, HCC-EduLink, to a) improve patients’ HCC-related disease and treatment knowledge; b) screen patients for social needs and substance use and refer to social work for linkage to local services; and c) use our multidisciplinary HCC tumor board to facilitate linkage to subspecialty HCC cancer care, improving access to curative therapies for Black patients with chronic liver disease and HCC.
Developing and Educational Intervention to Improve Disparities in HCC (Co-I)
$75,000 annually from the Office of Health Equity, IU Health 2022-2025
Ethics Committee - All IN for Health Advisory Board, Indiana CTSI, July 2021 - Present
Chair - Intersociety Group on Diversity Strategic Planning Committee, American Association for the Study of Liver Disease, April 2022 - Present
Member - Scientific Programming Committee, American Association for the Study of Liver Disease, April 2022 - Present